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Earlyperipheral parenteral nutrition on postoperative laparotomy patient with BCCA enriched solution, and moderate calory, with or without fat emulsion

Sunatrio S.
Department of Anesthesiology, Cipto Mangunkusumo Hospital,
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia


The aim of this study is 1) to evaluate the effectiveness of early peripheral parenteral nutrition using BCAA enriched solution and middle calory with or without fat emulsion, 2) to know whether early nutrition (6 hours postoperatively) may alter hepatic and kidney functions, 3) to know whether fat emulsion given simultaneously with other nutrients could lower the incidence of thrombophlebitis. Included in this study were 10 patients, 7 males and 3 females with age between 21 and 55 years and body weight between 45 and 55 kg. The patients were randomly allocated into two groups. Group A (n = 5) were receiving BCAA enriched solution (Amiparen, Otsuka) 1.0 g/kg BW/24 hours, glucose 3 g/kg BW/24 hours and electrolyte starting 6 hours after surgery after homeostasis and cardiovascular stability were achieved until the 4th postoperative day. The same formulations were given to group B (n = 5), where fat emulsion (Intralipid, Pfrimmer) of 1.3 g/kg BW/24 hours were added.

In all patients there were no significant changes in nitrogen and transferrin balances, SGOT and SGPT values. Significant changes were noted in prealbumin and albumin values. Thrombophlebitis occured in 40% of group A and nil in group B. It was concluded that BCAA enriched solution and middle calory was effective in maintaining nitrogen and transferrin balances. There were no negative impact on kidney and liver functions when parenteral nutrition was started 6 hours after surgery. Simultaneous administration of fat emulsion with another solution could lower the incidence of thrombo-phlebitis.



From "The 4th Congress of the PENSA Program & Abstract"
Taipei, Taiwan, December 9-12, 1998
Page : 39


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Update : January 2010