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Nutrition Support with Different Amino Acid Formulas in the Treatment of Various Disorders

Akira Okada
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan

The introduction of new therapeutic modalities such as parenteral and enteral nutrition support into clinical practice has induced a great improvement in therapeutic results in various kinds of catastrophic disorders. The establishment of nutrition support, along with the development of a multitude of diagnostic instruments and appliances, has made accurate metabolic monitoring possible, thereby leading to the possibility of adequately controlling metabolism of nutrients. Among a variety of nutrients, amino acid mixture was closely in investigated with regards to their metabolic specificity to principal organs and their metabolism in various morbid states. Amino acid infusion is nowadays believed to be initialized not only to supply the nitrogen source but also to improve various pathophysiologic conditions.

Different types of amino acid formulas are currently used in various clinical situations. These include formulas for patients with 1)hepatic failure 2)surgical in jury or sepsis 3)renal failure 4)intestinal failure 5)neonates (immaturity). In each of these formulas, certain amino acids such as branched chain amino acid (Ieucine, isoleucine, valine), glutamine, arginine, cystine or taurine are expected to play a role in metabolic control of various disorders.


From "The 7th Congress of the PENSA Abstract Book"
Bali, Indonesia, August 24-26, 2001
Page : 3


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Update : January 2010